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University of Bedfordshire
Park Square
Luton
Bedfordshire
UK, LU1 3JU
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PhD MSc BSc MRPharmS
Senior Lecturer in Pharmacology
My recent research is focused on applications of proteomic approaches in molecular toxicology. NanoLC-MS/MS and SELDI-TOF-MS are used to examine protein profiles of estrogen effects of environmental estrogenic compounds on human breast cancer.
Potential protein biomarkers are discovered and used to characterise dose response relationships of mixtures of estrogenic compounds. Molecular mechanism of estrogen effects and cell signalling pathway are explored by using label-free quantitative proteomics GeLC-MS/MS.
The latest application of these techniques is the identification and quantification of cytochrome P450 and Phase II metabolic enzymes in human native skin and 3D human skin models.
My previous research interests focussed on pharmaceutical sciences including antimicrobial chemotherapy, drug formulation and delivery systems, and pharmacokinetics and pharmacodynamics modelling.
