Position
Post-doctoral Research Development Fellow
Profile
Qualifications
- PhD Molecular and Cellular Physiology (Manchester Metropolitan University)
- MSc Physiology (Liverpool John Moores University)
- BSc (Hons) (Biology with Exercise Science)
Research Interests
The signalling mechanisms of striated muscle remodelling: Striated muscle (skeletal and cardiac muscle) undergoes remodelling, either positive or negative, in response to physiological and pathological stress. My research interest lies in dissecting the signalling mechanisms that regulate the remodelling processes using cellular and molecular approaches, and to test therapeutic strategies using in vitro and in vivo models.
Pubilications
- Al-Shanti N., Faulkner S.H., Saini A., Loram I. & Stewart, CE. (2011). A Semi-automated Programme for Tracking Myoblast Migration Following Mechanical Damage: Manipulation by Chemical Inhibitors. Cellular Physiology and Biochemistry, 27 XX-XX.
- Saini A., Al-Shanti N. & Stewart C.E. (2010). C2 skeletal myoblast survival, death, proliferation and differentiation: Regulation by Adra1d. Cellular Physiology and Biochemistry, 25 253-262.
- Al-Shanti N., Saini A. & Stewart C.E. (2009). Two-step vs One-Step RNA-to-Ct 2-Step And One-Step RNA-to-Ct 1-Step: Validity, accuracy, sensitivity and efficiency. The Journal of Biomolecular Techniques, 20(3) 172-179.
- Saini A., Faulkner S.H., Al-Shanti N. & Stewart C.E. (2009). Powerful signals for weak muscles. Ageing Research Reviews, 8(4) 251-267.
- Saini A., Al-Shanti N., Faulkner S.H. & Stewart C.E. (2008). Pro- and anti-apoptotic roles for IGF-I in TNF-?-induced apoptosis: a MAP kinase mediated mechanism. Growth Factors, 26(5) 239-253.
- Al-Shanti N., Saini A., Faulkner S.H. & Stewart C.E. (2007). Beneficial synergistic interactions of TNF-? and IL-6 in C2 skeletal myoblasts: A novel role for gp 130. Growth factors, 26(2) 61-73.
- Saini A., Al-Shanti N. & Stewart C.E. (2006). Waste management – cytokines, growth factors and cachexia. Cytokine and Growth Factor Reviews, 17(6) 475-486.
- Saini A. & Stewart C.E. (2006). Adult stem cells – the therapeutic potential of skeletal muscle. Current stem cell research and therapy, 1(2) 157-171.
- Burniston J.G., Saini A., Tan L-B & Goldspink D.F. (2005) Angiotensin II induces apoptosis in vivo in skeletal, as well as cardiac, muscle of the rat. Experimental Physiology, 90(5) 755-761.
- Burniston J.G., Saini A., Tan L-B & Goldspink D.F. (2005) Aldosterone induces myocyte apoptosis in the heart and skeletal muscles of rats in vivo. Journal of Molecular and Cellular Cardiology, 39(2) 395-399.
Contact Details
T: +44 (0)1234 793237
E:
amarjit.saini@beds.ac.uk
