Senior Lecturer in Microbiology

I am an experienced academic with an interest in the research and teaching of molecular microbiology.

I joined the University of Bedfordshire in the autumn of 2010 from King's College London, where I was Lecturer of Molecular Microbiology in the Dental Institute from 2003.

At KCL I supervised a number of PhD students investigating transport proteins and bacterial pathogenesis. I established this research interest at the University of Reading (1998-2003), where I investigated the role of transport proteins in Rhizobium leguminosarum, a bacterium responsible for nitrogen fixation in symbiosis with pea plants.

Other references

• @ArthurHosie
• LinkedIn

Qualifications

• PhD Microbiology, University of Glasgow, 1998
• BSc (Hons) Microbiology, University of Glasgow, 1991
• Postgraduate Certificate in Academic Practice, King's College London, 2005

Teaching Expertise

• Microbiology
• Applied Microbiology
• Molecular Biology
• MSc Biotechnology course leader

Research Interests

• Molecular Microbiology
• Bacterial pathogenesis
• Post-genomic microbiology

Research Projects

• In vivo induced antigens & virulence factors of Tannerella forsythia, a periodontal pathogen
• Carbohydrate transporters of Streptococcus mutans & Streptococcus pneumoniae
• Bacterial ATP binding cassette (ABC) transporters

External Roles

• Fellow of the Higher Education Academy

Publications

• S Basavanna, S Chimalapati, B Rubbo, J Yuste, A Hosie, G Thomas, JS Brown (2013) The effects of methionine acquisition and synthesis on Streptococcus pneumonia growth and virulence. PLOS One 8(1): e49638. Doi:10.1371/journal.pone.0049638
• J Prell, A Bourdes. S Kumar, S Lodwig, A Hosie, S Kinghorn, J White, P Poole (2010) Role of symbiotic auxotrophy in Rhizobium-legume symbioses. PLOS One 5 (11): e13933. doi:10.1371/ journal.pone.0013933.
• E Severi, AHF Hosie, J Hawkhead, GH Thomas (2010) Characterisation of a novel sialic acid transporter of the sodium solute symporter (SSS) family and in vivo comparison with known bacterial sialic acid transporters. FEMS Microbiology Letters 304 47-54.
• S Basavanna, S Khandavilli, J Yuste, JM Cohen, AHF Hosie, AJ Webb, GH Thomas, JS Brown (2009) Screening of Streptococcus pneumoniae ABC transporter mutants demonstrates that LivJHMGF, a branched chain amino acid ABC transporter, is necessary for disease pathogenesis., Infection and Immunity 77 (8), 3412-3423. 
• H Thompson, KA Homer, S Rao, V Booth, AHF Hosie, (2009) An orthologue of Bacteroidesfragilis NanH is the principal sialidase in Tannerella forsythia, Journal of Bacteriology 191 (11) 3263-3628.
• AJ Webb, KA Homer, AHF Hosie (2008) Two closely related ABC transporters in Streptococcus mutans are involved in di/oligosaccharide uptake. Journal of Bacteriology 190 (1) 168-178.
• AJ Webb, KA Homer, AHF Hosie (2007) A phosphoenolpyruvate-dependent phosphotransferase system is the principal maltose transporter in Streptococcus mutans. Journal of Bacteriology 189 3322-3327.
• E Allan, H Hussain, S Miah, ZK Ascott, MH Khwaja and AHF Hosie (2007) Genetic variation in comC, the gene encoding competence-stimulating peptide (CSP) in Streptococcus mutans. FEMS Microbiology Letters 268 47-51.
• TH Mauchline, JE Fowler, AK East, AL Sartor, R Zaheer, AHF Hosie, PS Poole & TM Finan (2006) Mapping the Sinorhizobium meliloti 1021 solute binding protein-dependent transportome. PNAS 103 17933-17938.
• A Webb and AHF Hosie (2006) A member of the carbohydrate uptake (CUT2) subfamily of ABC transporters is responsible for ribonucleoside uptake in Streptococcus mutans. Journal of Bacteriology188 8005-8012.
• MA Fox, JP White, AHF Hosie, EM Lodwig and PS Poole (2006) Osmotic upshift transiently inhibits uptake via ABC transporters in Gram-negative bacteria. Journal of Bacteriology 188 5304-5307.
• K Karunakaran, TH Mauchline, AHF Hosie, PS Poole (2005) A family of promoter probe vectors incorporating autofluorescent (AFP) and chromogenic reporter proteins for studying gene expression in Gram-negative bacteria. Microbiology 151 3249-3256.
• EM Lodwig*, AHF Hosie*, A Bourdès, K Findlay, D Allaway, R Karunakaran, JA Downie and PS Poole (2003) Amino-acid cycling drives nitrogen fixation in the legume-Rhizobium symbiosis. Nature 422 722-725.
  (*These authors contributed equally to this work)
• AHF Hosie, D Allaway, and PS Poole (2002) A monocarboxylate permease of Rhizobium leguminosarum is the first member of a new subfamily of transporters. Journal of Bacteriology 184 5436-5448.
• AHF Hosie, D Allaway, HA Dunsby, CS Galloway, and PS Poole (2002) Rhizobium leguminosarum has a second general amino acid permease with unusually broad substrate specificity and high similarity to branched-chain amino acid transporters (Bra/LIV) of the ABC family. Journal of Bacteriology 184 4071-4080.
• RA Carter, KH Yeoman, A Klein, AHF Hosie, G Sawers, PS Poole and AWB Johnston (2002) dpp genes of Rhizobiumleguminosarum specify uptake of delta-amino-levulinic acid. Molecular Plant-Microbe Interactions 15 69-74.
• AHF Hosie and PS Poole (2001) Bacterial ABC transporters of amino acids. Research in Microbiology 152 259-270.
• AHF Hosie, D Allaway, MA Jones, DL Walshaw, AWB Johnston and PS Poole (2001) Solute-binding protein-dependent ABC transporters are responsible for solute efflux in addition to solute uptake. Molecular Microbiology 40 1449-1459.
• AHF Hosie, S Gallacher and TH Birkbeck (1998) Transposon mutagenesis of marine bacteria which produce paralytic shellfish poisons. In Harmful Algae, VIII International Conference, pp. 299. Edited by B Reguera, J Blanco, ML Fernandez & T Wyatt. Vigo, Spain: Intergovernmental Oceanographic Commission of UNESCO.
• NF Inglis, K Stevenson, AHF Hosie and JM Sharp (1994) Complete sequence of the gene encoding the bacterioferritin subunit of Mycobacterium avium subspecies silvaticum. Gene 150 205-20

Contact Details

T: +44 (0)1582 743202
E: arthur.hosie@beds.ac.uk