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University of Bedfordshire
University Square
Luton
Bedfordshire
UK, LU1 3JU

Dr Maria Simon

CATS Faculty Technical Manager

I joined the School of Life Sciences in 2010 from Cancer Research UK where I was undertaking research on signal transduction in B cells. Before that, I was a Senior Scientist at GlaxoSmithKline, and a postdoctoral researcher at UCL. I completed my PhD at the National Institute for Medical Research, following a BSc (Hons) degree at Imperial College of Science, Technology and Medicine.

In 2018, I became a member of the CATS Faculty Executive Group overseeing the Technical and Administrative Staff across the 6 Schools of the Faculty.

I am responsible for overseeing the management of the resources and Facilities, of the 6 Schools, within the CATS Faculty. I sit on the university's Space Management Group. I assist the Faculty to deliver on a number of projects and provide specialist knowledge and advice to projects including the new STEM building.

As part of my broad remit, which includes administrative duties, I am responsible for ensuring that the Faculty is health and safety (H&S) compliant. I Chair the Life Science's Health and Safety (H&S) meetings and I sit on the university H&S committee.

I am a STEM Ambassador and a keen champion of Outreach activities within the Faculty.

Research Interests

My background is in immune cell signal transduction, investigating how proteins interact with each other to communicate signals within a cell to elicit an effect. I have 15 years' experience of working in this field in both industry and academia. I continue my research interests within the School, working with Prof Jan Domin.

Publications

  • Anti-Epileptic Effect of Ganoderma Lucidum Polysaccharides by Inhibition of Intracellular Calcium Accumulation and Stimulation of Expression of CaMKII α in Epileptic Hippocampal Neurons. Wang SQ, Li XJ, Qiu HB, Jiang ZM, Simon M, Ma XR, Liu L, Liu JX, Wang FF, Liang YF, Wu JM, Di WH, Zhou S. PLoS One. 2014 Jul 10;9(7):e102161. doi: 10.1371/journal.pone.0102161. eCollection 2014.
  • A role for the RNA pol II-associated PAF complex in AID-induced immune diversification. Willmann KL, Milosevic S, Pauklin S, Schmitz KM, Rangam G, Simon MT, Maslen S, Skehel M, Robert I, Heyer V, Schiavo E, Reina-San-Martin B & Petersen-Mahrt SK 2012. J Exp Med 209, 2099-2111.
  • AID in Immunodeficiency and Cancer in “DNA deamination and the Immune System”. Katharina Willmann, Sven Kracker, Maria T. Simon, Don-Marc-Franchini, Pauline Gardes, Anne Durandy, and Svend K. Petersen-Mahrt. 2010. Ed. Sebastian Fugmann, Marilyn Diaz and Nina Papava-siliou, Imperial College Press, London.
  • Constitutive activation of the Wnt/b-catenin signalling pathway in acute myeloid leukaemia. Simon, M., Grandage, V.L., Linch, D.C., and Khwaja, A. (2005) Oncogene, 24, pp.2410-2420
  • Distinct roles for the linker region tyrosines of Syk in FceRI signalling in primary mast cells. Simon, M., Vanes, L., Geahlen, R.L, and Tybulewicz, V.L.J. (2004) J. Biol. Chem. Vol 280, No. 6, pp.4510-4517
Bedfordshire University

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